Publications
Tornero-Écija A., Navas M.A., Muñoz-Braceras S., Vincent O. and Escalante R. (2023). Effect of rapamycin on lysosomal accumulation in a CRISPR/Cas9-based cellular model of VPS13A deficiency. Journal of Cellular and Molecular Medicine, doi: 10.1111/jcmm.17768
Tornero-Écija A., Zapata Del Baño A., Antón-Esteban L., Vincent O. and Escalante R.(2023). The association of lipid transfer protein VPS13A with endosomes is mediated by sorting nexin SNX5. Life Science Alliance, doi: 10.26508/lsa.202201852
Bueno-Arribas M, Blanca I, Cruz-Cuevas C, Escalante R, Navas MA and Vincent O. (2022). A conserved ATG2 binding site in WIPI4 and yeast Hsv2 is disrupted by mutations causing β-propeller protein-associated neurodegeneration. Human Molecular Genetics, doi: 10.1093/hmg/ddab225
Tornero-Écija A., Tábara L.C., Bueno-Arribas M., Antón-Esteban L., Navarro-Gómez C., Sánchez I., Vincent O. and Escalante R. (2022). A Dictyostelium model for BPAN disease reveals a functional relationship between the WDR45/WIPI4 homolog Wdr45l and Vmp1 in the regulation of autophagy-associated PtdIns3P and ER stress. Autophagy, 27, 1-17
Vincent O., Antón-Esteban L., Bueno-Arribas M., Tornero-Écija A., Navas M.A. and Escalante R. (2021). The WIPI gene family and neurodegenerative diseases: insights from Yeast and Dictyostelium models. Frontiers in Cell and Developmental Biology, doi: 10.3389/fcell.2021.737071
Klionsky D.J, et al (2021). Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy, 17, 1-382
Vincent O., Gutierrez-Nogués A., Trejo-Herrero A. and Navas M.A. (2020). A novel reverse two-hybrid method for the identification of missense mutations that disrupt protein-protein binding. Scientific Reports, 10, 21043
Muñoz-Braceras S., Tornero A, Vincent O. and Escalante R. (2019). VPS13A is closely associated with mitochondria and is required for efficient lysosomal degradation. Disease Models & Mechanisms, 12, dmm036681
Tábara L.C., Vincent O. and Escalante R. (2018). Evidence for an evolutionary relationship between Vmp1 and bacterial DedA proteins. The International Journal of Developmental Biology, 63, 67-71
Domínguez-Martín E., Hernández-Helvira M., Vincent O., Coria R. and Escalante R. (2018). Unfolding the Endoplasmic Reticulum of a Social Amoeba: Dictyostelium discoideum as a New Model for The Study of Endoplasmic Reticulum Stress. Cells, 7, E56
Tábara L.C., Vicente J.J., Biazik J., Eskelinen E.L., Vincent O., Escalante R. (2018). VMP1 marks ER subdomains enriched in phospholipid synthesizing enzymes and is required for phosphoinositide distribution. Traffic, 19, 624-638
Gutierrez-Nogués A., García-Herrero C.M., Oriola J., Vincent O. and Navas M.A. (2018). Functional characterization of MODY2 mutations in the Nuclear Export Signal of Glucokinase. BBA - Molecular Basis of Disease, 1864, 2385-2394
Domínguez-Martín E., Ongay-Larios L., Kawasaki L., Vincent O., Coello G., Coria R. and Escalante R. (2018). IreA controls endoplasmic reticulum stress-induced autophagy and survival through homeostasis recovery. Molecular and Cellular Biology, 38, e00054-18
Mesquita A, Cardenal-Muñoz E, Dominguez E, Muñoz-Braceras S, Nuñez-Corcuera B, Phillips BA, Tábara LC, Xiong Q, Coria R, Eichinger L, Golstein P, King JS, Soldati T, Vincent O and Escalante R. (2017). Autophagy in Dictyostelium: Mechanisms, regulation and disease in a simple biomedical model. Autophagy, 13, 24-40
Mesquita A., Tábara L.C., Martinez-Costa O., Santos N., Vincent O. and Escalante R. (2015). Dissecting the function of Atg1 complex in Dictyostelium autophagy reveals a connection with the pentose phosphate pathway enzyme transketolase. Open Biology, 9, 150088
Herrador A., Livas D., Soletto L., Becuwe M., Leon S. and Vincent O. (2015). Casein kinase 1 controls the activation threshold of an α-arrestin by multisite phosphorylation of the interdomain hinge. Molecular Biology of the Cell, 26, 2128-2138
Oriola J., Moreno F., Gutierrez-Nogués A., León S, García-Herrero C.M., Vincent O. and Navas M.A. (2015). Lack of glibenclamide response in a new case of neonatal diabetes caused by compound heterozygous glucokinase mild mutations. JIMD Reports, 20, 21-26
Herrador A., Leon S., Haguenauer-Tsapis R. and Vincent O. (2013). A mechanism for protein monoubiquitination dependent on a trans-acting ubiquitin binding domain. Journal of Biological Chemistry, 288, 16206-16211
Becuwe M., Herrador A, Haguenauer-Tsapis R., Vincent O. and Léon S. (2012). Ubiquitin-mediated regulation of endocytosis by proteins of the arrestin family. Biochemistry Research International, 2012, 242764
Becuwe M., Vieira N., Lara D., Gomes-Rezende J., Soares-Cunha C., Casal M., Haguenauer-Tsapis R., Vincent O., Paiva S. and Léon S. (2012). A molecular switch on a yeast arrestin-related protein connects glucose signaling to transporter endocitosis. Journal of Cellular Biology, 196, 247-259
Bañuelos C., Garciá-Rivera G., López-Reyes I., Mendoza L., Gonzalez-Robles A., Herranz S., Vincent O. and Orozco E. (2012). EhADH112 is a Bro1 domain-containing protein involved in the Entamoeba histolytica multivesicular bodies pathway. Journal of Biomedicine and Biotechnology, 2012, 657942
Garcia-Herrero C.M., Rubio-Cabezas O., Azriel S., Gutierrez-Nogués A., Vincent O., Argente J. and Navas M.A. (2012). Functional characterization of MODY2 mutations highlights the importance of the fine-tuning of glucokinase and its role in glucose sensing. Plos one, 7, e30518
Herrador A., Herranz S., Lara D. and Vincent O. Recruitment of the ESCRT machinery to a putative seven-transmembrane-domain receptor is mediated by an arrestin-related protein. Molecular and Cellular Biology, 30, 897-907
López-Reyes I., García-Rivera G.., Bañuelos C., Herranz S., Vincent O., López-Camarillo C., Marchat L.A. and Orozco E. (2010). Detection of the Endosomal Sorting Complex Required for Transport in Entamoeba histolytica and Characterization of the EhVps4 Protein. Journal of Biomedicine and Biotechnology, 2010, 890674
Galindo A., Hervás-Aguilar A., Rodríguez-Galán O., Vincent O., Arst HN., Tilburn J. and Peñalva M.A. (2007). PalC, one of two Bro1 domain proteins in the fungal pH signaling pathway, localizes to cortical structures and binds Vps32. Traffic, 8, 1346-1364
Garcia-Herrero CM, Galan M, Vincent O, Flandez B, Gargallo M, Delgado-Alvarez E, Blazquez E, Navas MA. (2007). Functional analysis of human glucokinase gene mutations causing MODY2: exploring the regulatory mechanisms of glucokinase activity. Diabetología, 50, 325-333
Galan M., Vincent O., Roncero I., Azriel S., Boix-Pallares P., Delgado-Alvarez E., Diaz-Cadorniga F., Blazquez E. and Navas M.A. (2006). Effects of novel maturity-onset diabetes of the young (MODY)-associated mutations on glucokinase activity and protein stability. Biochemical Journal, 393, 389-396
Chen C., Vincent O., Jin J., Weisz O.A. and Montelaro R.C. (2005). Functions of early (AP-2) and late (AIP1/ALIX) endocytic proteins in equine infectious anemia virus budding. Journal of Biological Chemistry, 280, 40474-40480
Herranz S., Rodríguez JM, Bussink HJ, Sánchez-Ferrero JC, Arst HN, Peñalva MA and Vincent O. (2005). Arrestin-related proteins mediate pH signaling in fungi. Proceedings of the National Academy of Sciences (PNAS), 112, 12141-12146
Vincent O., Rainbow L., Tilburn J., Arst H.N. and Peñalva M.A. (2003). YPXL/I Is a Protein Interaction Motif Recognized by Aspergillus PalA and Its Human Homologue, AIP1/Alix. Molecular and Cellular Biology, 23, 1647-1655
Vincent O., Townley R., Kuchin S. and Carlson M. (2001). Subcellular localization of the Snf1 kinase is regulated by specific beta subunits and a novel glucose signaling mechanism. Genes and Development, 15, 1104-1114
Vincent O., Kuchin S., Hong SP, Townley R., Vyas V. and Carlson M. (2001). Interaction of the Srb10 kinase with Sip4, a transcriptional activator of gluconeogenic genes in Saccharomyces cerevisiae. Molecular and Cellular Biology, 21, 5790-5796
Zaragoza O., Vincent O. and Gancedo J.M. (2001). Regulatory elements in the FBP1 promoter respond differently to glucose-dependent signals in Saccharomyces cerevisiae. Biochemical Journal, 359, 193-201
Enjalbert B, Parrou JL, Vincent O and Francois J. (2000). Mitochondrial respiratory mutants of Saccharomyces cerevisiae accumulate glycogen and readily mobilize it in a glucose-depleted medium. Microbiology, 146, 2685-2694
Vincent O. and Carlson M. (1999). Gal83 mediates the interaction of the Snf1 kinase complex with the transcription activator Sip4. EMBO Journal, 18, 6672-6681
Vincent O. and Carlson M. (1998). Sip4, a Snf1 kinase-dependent transcriptional activator, binds to the carbon source-responsive element of gluconeogenic genes. EMBO Journal, 17, 7002-7008
Vincent O. and Gancedo J.M. (1995). Analysis of positive elements sensitive to glucose in the promoter of the FBP1 gene from yeast. Journal of Biological Chemistry, 270, 12832-12838
Vincent O. and Gancedo J.M. (1995). Expression of a yeast gene can be blocked by insertion of short yeast DNA fragments between a UAS and the TATA box. Current Genetics, 27, 387-389
Salmon J.M., Vincent O., Mauricio J.C., Bely M. and Barre P. (1993). Sugar transport inhibition and apparent loss of activity in Saccharomyces cerevisiae as a major limiting factor of enological fermentations. American Journal of Enology and Viticulture, 44, 56-64
Mercado J.J., Vincent O. and Gancedo J.M. (1991). Regions in the promoter of the yeast FBP1 gene implicated in catabolite repression may bind the product of the regulatory gene MIG1. FEBS Letter, 291, 97-100